| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| SC-01 | REP | 341,879 | 51.9% | R+4.0 | |
| SC-02 | Joe WilsonREP | REP | 343,486 | 53.7% | R+7.6 |
| SC-03 | REP | 288,741 | 64.7% | R+29.5 | |
| SC-04 | Bob InglisREP | REP | 306,928 | 60.1% | R+23.2 |
| SC-05 | DEM | 306,285 | 61.6% | D+24.6 | |
| SC-06 | DEM | 286,571 | 67.5% | D+35.0 |