| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| PA-01 | DEM | 277,102 | 85.0% | D+69.9 | |
| PA-02 | Chaka FattahDEM | DEM | 356,386 | 89.3% | D+79.9 |
| PA-03 | REP | 302,514 | 54.8% | R+13.8 | |
| PA-04 | REP | 303,980 | 59.7% | R+25.3 | |
| PA-05 | REP | 282,465 | 62.9% | R+25.9 | |
| PA-06 | REP | 335,528 | 57.1% | R+14.3 | |
| PA-07 | REP | 353,451 | 59.4% | R+18.8 | |
| PA-08 | REP | 352,238 | 56.6% | R+13.2 | |
| PA-09 | Bill ShusterREP | REP | 274,305 | 61.7% | R+23.4 |
| PA-10 | REP | 273,790 | 65.6% | R+31.2 | |
| PA-11 | REP | 285,198 | 58.5% | R+17.1 | |
| PA-12 | REP | 338,941 | 51.7% | R+3.5 | |
| PA-13 | DEM | 303,819 | 69.1% | D+38.2 | |
| PA-14 | DEM | 327,634 | 76.9% | D+53.8 | |
| PA-15 | REP | 297,724 | 56.8% | R+13.5 | |
| PA-16 | REP | 284,781 | 54.9% | R+15.8 | |
| PA-17 | DEM | 267,601 | 60.3% | D+20.6 | |
| PA-18 | Tim MurphyREP | REP | 338,873 | 64.0% | R+27.9 |