| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| MO-01 | Wm Lacy ClayDEM | DEM | 314,024 | 75.5% | D+55.5 |
| MO-02 | Ann WagnerREP | REP | 413,296 | 58.5% | R+20.9 |
| MO-03 | REP | 368,333 | 67.8% | R+39.9 | |
| MO-04 | REP | 332,234 | 67.8% | R+40.0 | |
| MO-05 | DEM | 324,270 | 58.8% | D+20.7 | |
| MO-06 | Sam GravesREP | REP | 350,444 | 68.0% | R+39.6 |
| MO-07 | Billy LongREP | REP | 338,607 | 67.5% | R+40.1 |
| MO-08 | REP | 308,871 | 74.4% | R+51.7 |