| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| MO-01 | Lacy ClayDEM | DEM | 274,375 | 80.1% | D+63.4 |
| MO-02 | Ann WagnerREP | REP | 376,066 | 51.2% | R+4.0 |
| MO-03 | REP | 324,608 | 65.1% | R+32.2 | |
| MO-04 | REP | 293,316 | 64.8% | R+32.1 | |
| MO-05 | DEM | 283,785 | 61.7% | D+26.1 | |
| MO-06 | Sam GravesREP | REP | 305,409 | 65.4% | R+33.4 |
| MO-07 | Billy LongREP | REP | 296,455 | 66.2% | R+36.1 |
| MO-08 | REP | 264,399 | 73.4% | R+48.4 |