| District ▲ | Winner | Party | Votes | % | Margin |
|---|---|---|---|---|---|
| MO-01 | Wm Lacy ClayDEM | DEM | 279,277 | 86.9% | D+86.9 |
| MO-02 | W Todd AkinREP | REP | 372,972 | 62.3% | R+26.9 |
| MO-03 | DEM | 305,071 | 66.4% | D+36.0 | |
| MO-04 | Ike SkeltonDEM | DEM | 303,455 | 65.9% | D+31.8 |
| MO-05 | DEM | 306,415 | 64.4% | D+28.8 | |
| MO-06 | Sam GravesREP | REP | 330,699 | 59.4% | R+22.6 |
| MO-07 | Roy BluntREP | REP | 323,212 | 67.8% | R+39.6 |
| MO-08 | REP | 278,288 | 71.4% | R+45.3 | |
| MO-09 | REP | 322,095 | 50.0% | R+2.5 |